Tubulopathy is a potentially fatal chronic illness, often leading to death. It occurs when the blood stream is compromised by some sort of obstacle such as an infection, a clot or a deviated septum. The symptoms of tubulopathy can vary widely and depend on which areas of the body are affected. Common symptoms include persistent leg pain and tenderness (or even numbness), swelling, loss of appetite and nausea.
In some cases, symptoms begin suddenly and may be severe and intermittent. These can include a feeling of sickness, dizziness or lightheadedness. More severe symptoms, such as confusion or memory loss, can occur in rare instances. These symptoms usually develop slowly over time. One of the characteristic symptoms of kidney failure is the tendency for someone to feel weak or ill.
In addition to these classic symptoms, more obscure ones such as unexplained weight loss or lethargy may occur. The cause of tubulopathy is unknown, and it is not clear whether these symptoms are due to inflammation of blood vessels or infection. Many times, a patient with an acquired form of tubulopathy will display no outward signs. But internal examination may reveal some of the same conditions, such as high blood pressure and increased potassium levels. Sometimes, X-rays may show evidence of bone marrow tumors, which can be fatal if left untreated.
Tuberculosis is one of the most common infections that can lead to development of tubulopathy. People who have had exposure to tubercle bacilli are particularly susceptible to developing the disease. In addition, people who frequently suffer from allergic reactions or have a decreased immunity to infectious agents are also at higher risk.
Diagnosis of tubulopathy often involves an amniography. The amniographer can take a sample of the fluid in the body, such as from the lungs, to look for evidence of internal bleeding or infection. Sometimes, a CT scan or ultrasound may be used to further evaluate the severity of the symptoms. Treatment usually consists of bed rest and medication to reduce pain.
Infection caused by a virus or bacteria called Paget’s disease is one of the most common causes of end-stagetubulopathy. Treatment includes blood transfusions for people with extremely severe symptoms. Treatment for Paget’s disease usually involves prolonged hospitalization and antibiotic medication. It can also lead to life-threatening complications, such as shock coma.
Infection caused by a tumor or infection that blocks the pulmonary circulation is another common cause of end-stagetubulopathy. Treatment for obstructive pulmonary disease (COPD) generally requires oxygen therapy and other treatments. Patients with large tumors or those having a diagnosis of lung cancer may also be affected. Surgery is sometimes recommended as an alternative to conventional medicine in such patients. Antibiotics are sometimes prescribed in combination with these therapies in order to prevent the spread of infection.
Some symptoms of end-stagetubulopathy do not progress to the point of requiring surgery, although such patients may also have other, less serious conditions. Doctors treating such patients are more likely to treat them conservatively and try to improve their health as much as possible before resorting to surgery. However, if symptoms are present and left untreated, death may occur, even though this is rare.
Because symptoms of tubulopathy are often similar to those of many other diseases and illnesses, it is also important that people who develop such symptoms receive timely medical attention. Patients should seek treatment at the first sign of any such problems. They should also notify their doctors immediately if they develop a rash or any other unexplained skin irritation. In the case of jaundice, patients should also notify their doctors promptly, and they should stop consuming vitamin A, particularly in people with preexisting conditions such as jaundice.
One of the most common tests for diagnosing tubulopathy is the electrocardiogram or ECG. This test measures the electrical activity of the heart. The normal range for this activity is roughly four beats per minute, but in some cases it may increase or decrease significantly. If it shows abnormalities, such as a rapid increase or decrease in the heart’s electrical activity, a visit to the doctor is necessary.
Another common test is the blood test. The blood works to look for the presence of albumin in the patients’ blood. High levels of albumin have been associated with many different health conditions, including some forms of cancer. Doctors can also check for the proteins ESR and EGB in the blood samples. These are proteins produced by the endocrine system, and they are indicators of tubulopathy.
These are the main means of detecting tubulopathy. However, other symptoms can also help in diagnosing the condition. Patients experiencing vomiting, nausea, or abdominal pain should report these symptoms to their doctors right away. Patients who experience unusual fatigue, unexplained weight loss, or even diarrhea could also be suffering from tubulopathy. These symptoms can be quite telling, so it is recommended that they be reported immediately to a doctor.